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Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene

<p>Abstract</p> <p>Background</p> <p>DJ-1 forms part of the neuronal cellular defence mechanism against oxidative insults, due to its ability to undergo self-oxidation. Oxidative stress has been implicated in the pathogenesis of central nervous system damage in different neurodegenerative disorders...

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Hlavní autoři: Warnich Louise, Kinnear Craig, Venter Mauritz, van der Merwe Lize, Keyser Rowena J, Carr Jonathan, Bardien Soraya
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2009-10-01
Edice:BMC Medical Genetics
On-line přístup:http://www.biomedcentral.com/1471-2350/10/105
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