Preclinical Characterization of Efficacy and Pharmacodynamic Properties of Finotonlimab, a Humanized Anti-PD-1 Monoclonal Antibody

<b>Background/Objectives:</b> Finotonlimab (SCTI10A) is a humanized anti-PD-1 antibody tested in Phase III trials for several solid tumor types. <b>Methods</b>: This study characterized the in vitro and in vivo efficacy, Fc-mediated effector function, and non-clinical PK/PD properties of finotonlima...

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Detalhes bibliográficos

Principais autores:	Yunqi Yao, Xiaoning Yang, Jing Li, Erhong Guo, Huiyu Wang, Chunyun Sun, Zhangyong Hong, Xiao Zhang, Jilei Jia, Rui Wang, Juan Ma, Yaqi Dai, Mingjing Deng, Chulin Yu, Lingling Sun, Liangzhi Xie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-03-01
coleção:	Pharmaceuticals
Assuntos:	finotonlimab anti-PD-1 antibody preclinical characterization pharmacodynamics
Acesso em linha:	https://www.mdpi.com/1424-8247/18/3/395
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