Topical or oral antibiotics for children with acute otitis media presenting with ear discharge: study protocol of a randomised controlled non-inferiority trial

Background Around 15%–20% of children with acute otitis media present with ear discharge due to a spontaneous tear or perforation of the eardrum (AOMd). Current guidance recommends clinicians to consider oral antibiotics as first-line treatment in this condition. The opening in the eardrum however s...

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Principais autores:	Anne GM Schilder, Alastair D Hay, Marc J M Bonten, Michael V Moore, G Ardine de Wit, Debby Bogaert, Roderick P Venekamp, Roger A M J Damoiseaux, Elisabeth A M Sanders, Saskia Hullegie, Thijs M A van Dongen, Sanne Mulder, Willem van Schaik
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMJ Publishing Group 2021-12-01
coleção:	BMJ Open
Acesso em linha:	https://bmjopen.bmj.com/content/11/12/e052128.full
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