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Multicellular Liver Organoids: Generation and Importance of Diverse Specialized Cellular Components

Over 40,000 patients in the United States are estimated to suffer from end-stage liver disease and acute hepatic failure, for which liver transplantation is the only available therapy. Human primary hepatocytes (HPH) have not been employed as a therapeutic tool due to the difficulty in growing and e...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Giuseppe Ietto, Valentina Iori, Mattia Gritti, Davide Inversini, Angelita Costantino, Sofia Izunza Barba, Z. Gordon Jiang, Giulio Carcano, Daniela Dalla Gasperina, Giuseppe Pettinato
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-05-01
Schriftenreihe:Cells
Schlagworte:
endothelial cells
hepatic differentiation of hiPSCs
liver bioengineering
liver organoids
multicellular organoids
Online-Zugang:https://www.mdpi.com/2073-4409/12/10/1429
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