Quantitative targeted proteomics for occult cancer screening in patients with unprovoked venous thromboembolism: results from the prospective PLATO-VTE study

Background: About 5% of patients with unprovoked venous thromboembolism (VTE) have occult cancer. Despite standard cancer screening, 50% of cancers remain undetected. Objectives: We used quantitative targeted proteomics to identify novel cancer biomarkers among patients with unprovoked VTE. Methods:...

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Principais autores:	Noori A.M. Guman, Noémie Kraaijpoel, Frits I. Mulder, Marc Carrier, Luis Jara-Palomares, Marcello Di Nisio, Walter Ageno, Jan Beyer-Westendorf, Frederikus A. Klok, Thomas Vanassche, Johannes M.M.B. Otten, Benilde Cosmi, Mike J.L. Peters, Marije ten Wolde, Aurélien Delluc, Pieter W. Kamphuisen, Verónica Sánchez-López, Ettore Porreca, Jip Ramaker, Patrick M.M. Bossuyt, Harry R. Büller, Henri H. Versteeg, Bart J.M. van Vlijmen, Nick van Es, Yassene Mohammed
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-08-01
coleção:	Research and Practice in Thrombosis and Haemostasis
Assuntos:	early detection of cancer liquid biopsy neoplasms proteomics venous thromboembolism
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2475037925003425
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