Transcriptomics Reveals Discordant Lipid Metabolism Effects between In Vitro Models Exposed to Elafibranor and Liver Samples of NAFLD Patients after Bariatric Surgery

Background and aims: Non-alcoholic steatohepatitis (NASH) is a life-threatening stage of non-alcoholic fatty liver disease (NAFLD) for which no drugs have been approved. We have previously shown that human-derived hepatic in vitro models can be used to mimic key cellular mechanisms involved in the p...

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主要な著者:	Joost Boeckmans, Alexandra Gatzios, Anja Heymans, Matthias Rombaut, Vera Rogiers, Joery De Kock, Tamara Vanhaecke, Robim M. Rodrigues
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2022-03-01
シリーズ:	Cells
主題:	NASH NAFLD elafibranor in vitro hSKP-HPC HepaRG
オンライン･アクセス:	https://www.mdpi.com/2073-4409/11/5/893
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