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Metformin Attenuates Bone Cancer Pain by Reducing TRPV1 and ASIC3 Expression

Bone cancer pain (BCP) is a common pathologic pain associated with destruction of bone and pathological reconstruction of nervous system. Current treatment strategies in clinical is inadequate and have unacceptable side effects due to the unclear pathology mechanism. In the present study, we showed...

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Principais autores: He-Ya Qian, Fang Zhou, Rui Wu, Xiao-Jun Cao, Tao Zhu, Hao-Dong Yuan, Ya-Nan Chen, Ping-An Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-08-01
coleção:Frontiers in Pharmacology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2021.713944/full
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