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CLONAL SIGNATURES OF TELOMERE BIOLOGY DISORDERS AS SPECIFIC MARKERS FOR DISEASE DIAGNOSIS AND SURVEILLANCE

Introduction: In inherited marrow failure, clonal hematopoiesis (CH) are known to compensates for the intrinsic restricted cell fitness caused by a germline mutation (adaptive mechanisms) or associates with maladaptive mechanisms of clonal evolution, typically myelodysplastic syndromes or acute myel...

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Hauptverfasser: LFB Catto, EM Groarke, DV Clé, BA Santana, AP Azambuja, MM Oliveira, R Shalhoub, C Bomfim, NS Young, F Gutierrez-Rodrigues, R Calado
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2023-10-01
Schriftenreihe:Hematology, Transfusion and Cell Therapy
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S253113792300281X
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