Safety and effectiveness of post-trastuzumab deruxtecan regimens in patients with HER2-positive metastatic breast cancer who discontinued trastuzumab deruxtecan due to interstitial lung disease

Background: The real-world EN-SEMBLE (jRCT1030220506) study investigated the effectiveness and safety of treatments subsequent to trastuzumab deruxtecan (T-DXd) in patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (mBC). This post hoc analysis provides i...

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Hlavní autoři:	Junji Tsurutani, Kazuki Nozawa, Toru Mukohara, Tetsuhiko Taira, Akiyo Yoshimura, Shigenori E. Nagai, Jun Hashimoto, Kazuo Matsuura, Toshiro Mizuno, Yoshiaki Shinden, Mitsugu Yamamoto, Toshimi Takano, Makoto Wakahara, Hirofumi Terakawa, Takashi Yamanaka, Yasuyuki Kojima, Takahiro Nakayama, Yuji Hirakawa, Kazuhito Shiosakai, Hiroji Iwata
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-04-01
Edice:	Breast
Témata:	Interstitial lung disease Metastatic breast cancer Trastuzumab deruxtecan Subsequent treatment
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0960977626000329
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