Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival

In chronic lymphocytic leukemia (CLL), the acquisition of new genomic aberrations during the disease course (clonal evolution) is thought to be an infrequent phenomenon but comprehensive analyses are limited. Genomic aberrations were analyzed by fluorescence in situ hybridization (FISH) at various t...

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Detalhes bibliográficos

Principais autores:	Stephan Stilgenbauer, Sandrine Sander, Lars Bullinger, Axel Benner, Elke Leupolt, Dirk Winkler, Alexander Kröber, Dirk Kienle, Peter Lichter, Hartmut Döhner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Ferrata Storti Foundation 2007-09-01
Colecção:	Haematologica
Acesso em linha:	https://haematologica.org/article/view/4566
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