Huntington’s Disease: A Review of the Known PET Imaging Biomarkers and Targeting Radiotracers
Huntington’s disease (HD) is a fatal neurodegenerative disease caused by a CAG expansion mutation in the <i>huntingtin</i> gene. As a result, intranuclear inclusions of mutant huntingtin protein are formed, which damage striatal medium spiny neurons (MSNs). A review of Positron Emission Tomogr...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI AG
2020-01-01
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| Schriftenreihe: | Molecules |
| Schlagworte: | |
| Online-Zugang: | https://www.mdpi.com/1420-3049/25/3/482 |
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