pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy

Avidin and avidin-like proteins are widely used in numerous techniques since the avidin-biotin interaction is known to be very robust and reliable. Within this study, we investigated this bond at the molecular level under harsh conditions ranging from very low to very high pH values. We compared avi...

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主要な著者:	Melanie Köhler, Andreas Karner, Michael Leitner, Vesa P. Hytönen, Markku Kulomaa, Peter Hinterdorfer, Andreas Ebner
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2014-08-01
シリーズ:	Molecules
主題:	avidin mutant avidin-biotin force spectroscopy molecular recognition pH dependence single molecules biophysics
オンライン･アクセス:	http://www.mdpi.com/1420-3049/19/8/12531
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