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Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells.

BACKGROUND: Fascin is an actin-bundling protein that is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. How fascin-1 transcription is activated in carcinoma cells is largely unknown, although...

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Hlavní autoři: Yosuke Hashimoto, David W Loftis, Josephine C Adams
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2009-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC2661145?pdf=render
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