CpG‐Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2‐Mediated Remodeling of Tumor‐Associated Macrophages

Abstract CpG oligodeoxynucleotides (CpG), as an immunoadjuvant, can facilitate the transformation of tumor‐associated macrophages (TAMs)into tumoricidal M1 macrophages. However, the accumulation of free CpG in tumor tissues remains a substantial challenge. To address this, a nanovaccine (PLGA‐CpG@ID...

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Главные авторы:	Jiaqiang Xiong, Juyuan Huang, Hanxiao Xu, Qiuji Wu, Jiahui Zhao, Yurou Chen, Guanlan Fan, Haotong Guan, Rourou Xiao, Zhaojin He, Siqi Wu, Wenliang Ouyang, Shixuan Wang, Lu Zhang, Peng Xia, Wei Zhang, Meng Wu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2025-04-01
Серии:	Advanced Science
Предметы:	Gbp2 immunotherapy nanovaccine ovarian cancer TAMs
Online-ссылка:	https://doi.org/10.1002/advs.202412881
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