Modular Synthesis and Biological Investigation of 5-Hydroxymethyl Dibenzyl Butyrolactones and Related Lignans

Dibenzyl butyrolactone lignans are well known for their excellent biological properties, particularly for their notable anti-proliferative activities. Herein we report a novel, efficient, convergent synthesis of dibenzyl butyrolactone lignans utilizing the acyl-Claisen rearrangement to stereoselecti...

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Autori principali:	Samuel J. Davidson, Lisa I. Pilkington, Nina C. Dempsey-Hibbert, Mohamed El-Mohtadi, Shiying Tang, Thomas Wainwright, Kathryn A. Whitehead, David Barker
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2018-11-01
Serie:	Molecules
Soggetti:	lignans dibenzyl butyrolactones anti-proliferative acyl-Claisen stereoselective synthesis
Accesso online:	https://www.mdpi.com/1420-3049/23/12/3057
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