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Bacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters

Summary: Gut microbes can synthesize multiple neuro-active metabolites. We profiled neuro-active compounds produced by the gut commensal Bacteroides ovatus in vitro and in vivo by LC-MS/MS. We found that B. ovatus generates acetic acid, propionic acid, isobutyric acid, and isovaleric acid. In vitro,...

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Autori principali: Thomas D. Horvath, Faith D. Ihekweazu, Sigmund J. Haidacher, Wenly Ruan, Kristen A. Engevik, Robert Fultz, Kathleen M. Hoch, Ruth Ann Luna, Numan Oezguen, Jennifer K. Spinler, Anthony M. Haag, James Versalovic, Melinda A. Engevik
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2022-05-01
Serie:iScience
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Accesso online:http://www.sciencedirect.com/science/article/pii/S258900422200428X
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