Orexin induces the production of an endocannabinoid-derived lysophosphatidic acid eliciting hypothalamic synaptic loss in obesity

Objective: Orexin-A (OX-A) is a neuropeptide produced selectively by neurons of the lateral hypothalamus. It exerts powerful control over brain function and physiology by regulating energy homeostasis and complex behaviors linked to arousal. Under conditions of chronic or acute brain leptin signalin...

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Egile Nagusiak:	Alba Clara Fernández-Rilo, Nicola Forte, Letizia Palomba, Lea Tunisi, Fabiana Piscitelli, Roberta Imperatore, Alfonso Di Costanzo, Vincenzo Di Marzo, Luigia Cristino
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2023-06-01
Saila:	Molecular Metabolism
Gaiak:	Hypothalamus Obesity α-MSH Orexin/hypocretin 2-Arachidonoyl-glycerol 2-AG
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2212877823000479
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