Impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca2+ handling across the adult lifespan in men

Summary: Aging-related muscle atrophy and weakness contribute to loss of mobility, falls, and disability. Mitochondrial dysfunction is widely considered a key contributing mechanism to muscle aging. However, mounting evidence positions physical activity as a confounding factor, making unclear whethe...

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Podrobná bibliografie

Hlavní autoři:	Marina Cefis, Vincent Marcangeli, Rami Hammad, Jordan Granet, Jean-Philippe Leduc-Gaudet, Pierrette Gaudreau, Caroline Trumpff, Qiuhan Huang, Martin Picard, Mylène Aubertin-Leheudre, Marc Bélanger, Richard Robitaille, José A. Morais, Gilles Gouspillou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-02-01
Edice:	Cell Reports Medicine
Témata:	skeletal muscle aging sarcopenia mitochondria muscle atrophy and weakness calcium retention capacity mitochondrial permeability transition pore
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2666379125000412
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