A One-step strategy to target essential factors with auxin-inducible degron system in mouse embryonic stem cells

The self-renewal and pluripotency of embryonic stem cells (ESCs) are conferred by networks including transcription factors and histone modifiers. The Auxin-inducible degron (AID) system can rapidly and reversibly degrade its target proteins and is becoming a powerful tool to explore novel function o...

Descripció completa

Dades bibliogràfiques

Autors principals:	Jingsheng Li, Chunhong Dai, Wenyan Xie, Heyao Zhang, Xin Huang, Constantinos Chronis, Ying Ye, Wensheng Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-08-01
Col·lecció:	Frontiers in Cell and Developmental Biology
Matèries:	pluripotency embryonic stem cells chromatin modifiers auxin-inducible degron differentiation
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcell.2022.964119/full
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!