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Loss of Beta‐Cell Identity and Function as a Mechanism of Secondary Failure of Sulfonylurea Therapy in Diabetes

ABSTRACT Sulfonylureas, commonly used to treat type 2 diabetes (T2D), often lose effectiveness over time when used as monotherapy; however, the underlying mechanisms remain unclear. To investigate the mechanisms of sulfonylurea failure, glibenclamide‐releasing pellets were implanted in KK mice, a po...

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Váldodahkkit: Sumit Patel, Zihan Yan, Maria S. Remedi
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Wiley 2026-02-01
Ráidu:MedComm
Fáttát:
Liŋkkat:https://doi.org/10.1002/mco2.70588
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