Highly sensitive analysis of sterol profiles in human serum by LC-ESI-MS/MSs⃞

We have developed a highly sensitive and specific method for the analysis of serum sterol profiles. Sterols in 1 μl of dried serum were derivatized into picolinyl esters (3β-picolinate) and analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) using the electrospray ionization (ESI)...

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Bibliographic Details

Main Authors:	Akira Honda, Kouwa Yamashita, Hiroshi Miyazaki, Mutsumi Shirai, Tadashi Ikegami, Guorong Xu, Mitsuteru Numazawa, Takashi Hara, Yasushi Matsuzaki
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2008-09-01
Series:	Journal of Lipid Research
Subjects:	cholestanol cholesterol precursors congenital birth defect liquid chromatography-electrospray ionization-tandem mass spectrometry picolinic acid plant sterols
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520346745
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