Immune cell proportions correlate with clinicogenomic features and ex vivo drug responses in acute myeloid leukemia

IntroductionThe implementation of small-molecule and immunotherapies in acute myeloid leukemia (AML) has been challenging due to genetic and epigenetic variability amongst patients. There are many potential mechanisms by which immune cells could influence small-molecule or immunotherapy responses, y...

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Principais autores:	Kyle A. Romine, Daniel Bottomly, William Yashar, Nicola Long, Matthew Viehdorfer, Shannon K. McWeeney, Jeffrey W. Tyner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-06-01
Colecção:	Frontiers in Oncology
Assuntos:	AML – acute myeloid leukemia immune therapeutics checkpoint inhibition therapy RNAseq analysis functional genomic data
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1192829/full
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