Molecular Dynamics Simulation of Drug Solubilization Behavior in Surfactant and Cosolvent Injections

Surfactants and cosolvents are often combined to solubilize insoluble drugs in commercially available intravenous formulations to achieve better solubilization. In this study, six marketed parenteral formulations with surfactants and cosolvents were investigated on the aggregation processes of micel...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Meiqi He, Wenwen Zheng, Nannan Wang, Hanlu Gao, Defang Ouyang, Zunnan Huang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2022-11-01
Цуврал:	Pharmaceutics
Нөхцлүүд:	solubilization surfactant cosolvent molecular dynamics simulation water-insoluble drug
Онлайн хандалт:	https://www.mdpi.com/1999-4923/14/11/2366
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!