The <italic toggle="yes">Aspergillus fumigatus</italic> CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect

ABSTRACT Aspergillus fumigatus is an opportunistic fungal pathogen that causes invasive aspergillosis (IA), a life-threatening disease in immunocompromised humans. The echinocandin caspofungin, adopted as a second-line therapy in combating IA, is a β-1,3-glucan synthase inhibitor, which, when used i...

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Detalhes bibliográficos

Principais autores:	Laure Nicolas Annick Ries, Marina Campos Rocha, Patrícia Alves de Castro, Rafael Silva-Rocha, Roberto Nascimento Silva, Fernanda Zanolli Freitas, Leandro José de Assis, Maria Célia Bertolini, Iran Malavazi, Gustavo H. Goldman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2017-07-01
coleção:	mBio
Assuntos:	Aspergillus fumigatus cell wall integrity pathway caspofungin paradoxical effect
Acesso em linha:	https://journals.asm.org/doi/10.1128/mBio.00705-17
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