Epigenetic modifications in hematopoietic ecosystem: a key tuner from homeostasis to acute myeloid leukemia
Hematopoietic stem cells (HSCs) maintain homeostasis in the hematopoietic ecosystem, which is tightly regulated at multiple layers. Acute myeloid leukemia (AML) is a severe hematologic malignancy driven by genetic and epigenetic changes that lead to the transformation of leukemia stem cells (LSCs)....
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| Principais autores: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wolters Kluwer Health
2024-10-01
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| Serier: | Blood Science |
| Online adgang: | http://journals.lww.com/10.1097/BS9.0000000000000206 |
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