A qPCR Method for AAV Genome Titer with ddPCR-Level of Accuracy and Precision
Recombinant adeno-associated virus (rAAV) is one of the main vectors used in gene therapy. An accurate genome titer is not only critical for clinical dosing, but also a prerequisite for many analytical assays for AAV product characterization. AAV genome titer is traditionally determined by qPCR; how...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020-12-01
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| coleção: | Molecular Therapy: Methods & Clinical Development |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2329050120302023 |
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