Assessment of a polygenic hazard score for the onset of pre-clinical Alzheimer’s disease

Abstract Background With a growing number of loci associated with late-onset (sporadic) Alzheimer’s disease (AD), the polygenic contribution to AD is now well established. The development of polygenic risk score approaches have shown promising results for identifying individuals at higher risk of de...

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Bibliografische gegevens
Hoofdauteurs:	Michael Vacher, Vincent Doré, Tenielle Porter, Lidija Milicic, Victor L. Villemagne, Pierrick Bourgeat, Sam C. Burnham, Timothy Cox, Colin L. Masters, Christopher C. Rowe, Jurgen Fripp, James D. Doecke, Simon M. Laws
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2022-05-01
Reeks:	BMC Genomics
Onderwerpen:	Alzheimer’s disease Polygenic hazard score Brain atrophy AD onset
Online toegang:	https://doi.org/10.1186/s12864-022-08617-2
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Assessment of a polygenic hazard score for the onset of pre-clinical Alzheimer’s disease

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