TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2

Abstract Background The fate of hydrogen peroxide (H2O2) in the endoplasmic reticulum (ER) has been inferred indirectly from the activity of ER-localized thiol oxidases and peroxiredoxins, in vitro, and the consequences of their genetic manipulation, in vivo. Over the years hints have suggested that...

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Autors principals:	Eduardo Pinho Melo, Carlos Lopes, Peter Gollwitzer, Stephan Lortz, Sigurd Lenzen, Ilir Mehmeti, Clemens F. Kaminski, David Ron, Edward Avezov
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2017-03-01
Col·lecció:	BMC Biology
Matèries:	Endoplasmic reticulum Redox H2O2 probe Hydrogen peroxide Glutathione Fluorescent protein sensor
Accés en línia:	http://link.springer.com/article/10.1186/s12915-017-0367-5
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