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Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma

Senescence can have beneficial and detrimental impact on cancer progression depending on the cellular context. Here the authors show that NRF2 regulates the senescence phenotype in malignant cells which consequently contribute to glioblastoma progression.

Wedi'i Gadw mewn:
Prif Awduron: Rana Salam, Alexa Saliou, Franck Bielle, Mathilde Bertrand, Christophe Antoniewski, Catherine Carpentier, Agusti Alentorn, Laurent Capelle, Marc Sanson, Emmanuelle Huillard, Léa Bellenger, Justine Guégan, Isabelle Le Roux
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2023-01-01
Cyfres:Nature Communications
Mynediad Ar-lein:https://doi.org/10.1038/s41467-023-36124-9
Tagiau: Ychwanegu Tag
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