Multinucleated Giant Cells: Current Insights in Phenotype, Biological Activities, and Mechanism of Formation

Monocytes and macrophages are innate immune cells with diverse functions ranging from phagocytosis of microorganisms to forming a bridge with the adaptive immune system. A lesser-known attribute of macrophages is their ability to fuse with each other to form multinucleated giant cells. Based on thei...

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Hlavní autoři:	Kourosh Ahmadzadeh, Margot Vanoppen, Carlos D. Rose, Patrick Matthys, Carine Helena Wouters
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-04-01
Edice:	Frontiers in Cell and Developmental Biology
Témata:	multinucleated giant cell (MGC) osteoclast foreign body giant cell (FBGC) Langhans giant cell (LGC) macrophage cell fusion
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcell.2022.873226/full
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