Optimization of simvastatin transdermal patch for hyperlipidemia treatment in rat model
Abstract Objective Biopharmaceutics Classification System says that simvastatin (SMV) is a Class II drug with low bioavailability (5%). This is because it dissolves slowly and is broken down a lot in the first pass. Simvastatin transdermal patches were produced as part of this study's aim to treat h...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SpringerOpen
2024-02-01
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| Schriftenreihe: | Future Journal of Pharmaceutical Sciences |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s43094-024-00606-4 |
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