Polymorphisms of α1-antitrypsin and Interleukin-6 genes and the progression of hepatic cirrhosis in patients with a hepatitis C virus infection

Hepatitis C virus (HCV) infection represents a serious health problem. The –174 G/C mutation in the pro inflammatory cytokine interleukin-6 (IL-6) is associated with developing liver diseases. Likewise, the S and Z mutations in the serine protease inhibitor α1-antitrypsin (A1AT) are associated with...

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Autori principali:	Motawi T, Shaker OG, Hussein RM, Houssen M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Sciendo 2016-12-01
Serie:	Balkan Journal of Medical Genetics
Soggetti:	α1 antitrypsin (a1at) cirrhosis inter-leukin 6 (il-6) hepatitis c virus (hcv) infection polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) polymorphism
Accesso online:	https://doi.org/10.1515/bjmg-2016-0034
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