Adaptation of H2N2 influenza viruses with different receptor specificity to MDCK cells: opportunities for the development of a cell-based vaccine against pandemic H2N2 influenza

Introduction. H2N2 influenza viruses caused a pandemic in 1957 due to the adaptation of avian influenza hemagglutinin from avian-type α2,3 to human-type α2,6 receptor specificity. These viruses have not circulated among humans for more than 50 years but are still found in avian reservoirs, indicatin...

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Главные авторы:	Victoria A. Matyushenko, Arina D. Kostromitina, Larisa G. Rudenko, Irina N. Isakova-Sivak
Формат:	Artigo
Язык:	Russo
Опубликовано:	Central Research Institute for Epidemiology 2025-03-01
Серии:	Журнал микробиологии, эпидемиологии и иммунобиологии
Предметы:	influenza virus h2n2 receptor specificity adaptation mdck cells live attenuated influenza vaccine immunogenicity
Online-ссылка:	https://microbiol.crie.ru/jour/article/viewFile/18803/1575
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