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Regulation of Hematopoietic Cell Development and Function Through Phosphoinositides

One of the most paramount receptor-induced signal transduction mechanisms in hematopoietic cells is production of the lipid second messenger phosphatidylinositol(3,4,5)trisphosphate (PIP3) by class I phosphoinositide 3 kinases (PI3K). Defective PIP3 signaling impairs almost every aspect of hematopoi...

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Autors principals: Mila Elich, Karsten Sauer
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018-05-01
Col·lecció:Frontiers in Immunology
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Accés en línia:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00931/full
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