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Modulation of CCR2/CCL2 molecular axis in the expansion and rupture of abdominal aortic aneurysms

The CCR2/CCL2 molecular axis is a critical mediator of abdominal aortic aneurysm (AAA) pathogenesis. It has been demonstrated to drive chronic inflammation, extracellular matrix degradation, and vascular remodeling through the recruitment and activation of monocytes/macrophages and other immune cell...

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Principais autores: Ryan Wahidi, Santiago Elizondo-Benedetto, Ryan Catlett, Bera Koklu, Mohamed A. Zayed
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2026-02-01
Serija:Frontiers in Cardiovascular Medicine
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Online dostop:https://www.frontiersin.org/articles/10.3389/fcvm.2026.1772497/full
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