Engineering Dual Active Sites and Defect Structure in Nanozymes to Reprogram Jawbone Microenvironment for Osteoradionecrosis Therapy

Abstract Four to eight percent of patients with head and neck cancer will develop osteoradionecrosis of the jaw (ORNJ) after radiotherapy. Various radiation‐induced tissue injuries are associated with reactive oxygen and nitrogen species (RONS) overproduction. Herein, Fe doping is used in VOx (Fe‐VO...

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Hlavní autoři:	Zheng Cheng, Yuchen Wang, Haobo Lin, Ziyu Chen, Ran Qin, Tianxiao Wang, Hang Xu, Yifei Du, Hua Yuan, Yongchu Pan, Huijun Jiang, Xinquan Jiang, Jiandong Jiang, Fan Wu, Yuli Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-02-01
Edice:	Advanced Science
Témata:	enzyme‐like performance mitophagy nanozymes osteoradionecrosis of the jaw reactive oxygen and nitrogen species
On-line přístup:	https://doi.org/10.1002/advs.202413215
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