SIRT1/PGC-1α/PPAR-γ Correlate With Hypoxia-Induced Chemoresistance in Non-Small Cell Lung Cancer

Resistance is the major cause of treatment failure and disease progression in non-small cell lung cancer (NSCLC). There is evidence that hypoxia is a key microenvironmental stress associated with resistance to cisplatin, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), and...

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Detalhes bibliográficos

Principais autores:	Rui Xu, Xin Luo, Xuan Ye, Huan Li, Hongyue Liu, Qiong Du, Qing Zhai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-07-01
coleção:	Frontiers in Oncology
Assuntos:	non-small cell lung cancer chemoresistance SIRT1 PGC-1α PPAR-γ
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2021.682762/full
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