NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase
Abstract Background Aerobic glycolysis, a hallmark of cancer, is characterized by increased metabolism of glucose and production of lactate in normaxia. Recently, pyruvate kinase M2 (PKM2) has been identified as a key player for regulating aerobic glycolysis and promoting tumor cell proliferation an...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2017-01-01
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| Seria: | Journal of Hematology & Oncology |
| Hasła przedmiotowe: | |
| Dostęp online: | http://link.springer.com/article/10.1186/s13045-017-0392-4 |
| Etykiety: |
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