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Curcumin enhances bedaquiline’s efficacy against Mycobacterium abscessus: in vitro and in vivo evidence

ABSTRACT In this study, we describe the combined effects of bedaquiline (BDQ) and the natural product curcumin (CUR) on Mycobacterium abscessus. In both in vitro and in vivo experiments, CUR enhanced BDQ’s inhibitory effect. This combination reduced M. abscessus survival under nutrient-deprived, hyp...

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Bibliografische gegevens
Hoofdauteurs: Dan Luo, Weile Xie, Zhe Wang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2025-05-01
Reeks:Microbiology Spectrum
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Online toegang:https://journals.asm.org/doi/10.1128/spectrum.02295-24
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