Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by <named-content content-type="genus-species">Candida albicans</named-content> Hyphae

ABSTRACT Candida albicans is an opportunistic fungal pathogen that can cause life-threatening infections, particularly in immunocompromised patients. C. albicans induced activation of the Nlrp3 inflammasome, leading to secretion of bioactive interleukin 1β (IL-1β) is a crucial myeloid cell immune re...

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Detalhes bibliográficos

Principais autores:	Ona Rogiers, Ulrika C. Frising, Soňa Kucharíková, Mary Ann Jabra-Rizk, Geert van Loo, Patrick Van Dijck, Andy Wullaert
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2019-02-01
coleção:	mBio
Assuntos:	Candida albicans NLRP3 candidalysin inflammasome primary macrophages
Acesso em linha:	https://journals.asm.org/doi/10.1128/mBio.02221-18
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