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Enhancing implant surfaces: mechanical stability and cytocompatibility of DNase I coatings deposited by alternating current electrophoretic deposition

Deoxyribonuclease I (DNase I) is an enzyme that hydrolyzes the phosphodiester bonds in the DNA backbone, enabling efficient DNA degradation. This activity is particularly relevant for degrading extracellular DNA (eDNA), a key structural component of the biofilm extracellular matrix that enhances bac...

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Principais autores: Merve Kübra Aktan, Naiera Zayed, Aydan Yadigarli, Manuela Sonja Killian, Rob Lavigne, Wim Teughels, Annabel Braem
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-01-01
Serier:Frontiers in Bioengineering and Biotechnology
Fag:
coatings
cytocompatibility
deoxyribonuclease (DNase)
electrophoretic deposition (EPD)
mechanical stability
Online adgang:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1738602/full
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