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Discovery of novel serum peptide biomarkers for cholangiocarcinoma recurrence through MALDI-TOF MS and LC–MS/MS peptidome analysis

Abstract Cholangiocarcinoma (CCA) is an aggressive cancer originating from bile duct epithelial cells, with a high rate of recurrence following surgical resection. Recurrence is categorized as early linked to aggressive tumor biology than late recurrence. This study aimed to identify novel peptide m...

Deskribapen osoa

Gorde:
Egile Nagusiak: Vasin Thanasukarn, Piya Prajumwongs, Nattha Muangritdech, Watcharin Loilome, Nisana Namwat, Poramate Klanrit, Arporn Wangwiwatsin, Sawanya Charoenlappanit, Janthima Jaresitthikunchai, Sittiruk Roytrakul, Attapol Titapun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2025-01-01
Saila:Scientific Reports
Gaiak:
Cholangiocarcinoma
Recurrence
Peptidome
Peptide biomarker
MALDI-TOF MS
LC–MS/MS
Sarrera elektronikoa:https://doi.org/10.1038/s41598-025-87124-2
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