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Improving cellular phylogenies through the integrated use of mutation order and optimality principles

The study of tumor evolution is being revolutionalized by single-cell sequencing technologies that survey the somatic variation of cancer cells. In these endeavors, reliable inference of the evolutionary relationship of single cells is a key step. However, single-cell sequences contain many errors a...

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Príomhchruthaitheoirí: Sayaka Miura, Tenzin Dolker, Maxwell Sanderford, Sudhir Kumar
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Association for the Advancement of Science (AAAS) 2023-01-01
Sraith:Computational and Structural Biotechnology Journal
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Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S2001037023002635
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