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Screening potential diagnostic biomarkers for PLA2R‑associated idiopathic membranous nephropathy by WGCNA analysis and LASSO algorithm

Adult nephrotic syndrome is primarily caused by membranous nephropathy (MN), with idiopathic membranous nephropathy (IMN) being a prominent subtype. The onset of phospholipase A2 receptor (PLA2R1)-associated IMN is critically linked to M-type PLA2R1 exposure, yet the mechanism underlying glomerular...

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Principais autores: Jinxu Huang, Yaqing Huang, Xiaoling Zeng, Yuhong Zhang, Junneng Zhang, Qingchu Hong, Yongtiao Peng
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2025-12-01
Serier:Renal Failure
Fag:
PLA2R
idiopathic membranous nephropathy
WGCNA
LASSO
Online adgang:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2438859
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