Roles of oxidative stress/JNK/ERK signals in paraquat-triggered hepatic apoptosis

Paraquat (PQ), a toxic and nonselective bipyridyl herbicide, is one of the most extensively used pesticides in agricultural countries. In addition to pneumotoxicity, the liver is an important target organ for PQ poisoning in humans. However, the mechanism of PQ in hepatotoxicity remains unclear. In...

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Detalhes bibliográficos

Principais autores:	Kuan-I Lee, Kai-Min Fang, Chun-Ying Kuo, Chun-Fa Huang, Shing-Hwa Liu, Jui-Ming Liu, Wei-Cheng Lai, Kai-Chih Chang, Chin-Chuan Su, Ya-Wen Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-01-01
coleção:	Current Research in Toxicology
Assuntos:	Paraquat Hepatotoxicity Apoptosis Oxidative stress JNK ERK1/2
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2666027X24000082
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