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Serum but not cerebrospinal fluid levels of allantoin are increased in de novo Parkinson’s disease

Abstract Oxidative stress supposedly plays a role in the pathogenesis of Parkinson’s disease (PD). Uric acid (UA), a powerful antioxidant, is lowered in PD while allantoin, the oxidation product of UA and known biomarker of oxidative stress, was not systematically studied in PD. We aim to compare se...

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Detalhes bibliográficos
Principais autores: Lenka Hasíková, Jakub Závada, Tereza Serranová, Petr Kozlík, Květa Kalíková, Lenka Kotačková, Jiří Trnka, David Zogala, Karel Šonka, Evžen Růžička, Petr Dušek
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2023-04-01
coleção:npj Parkinson's Disease
Acesso em linha:https://doi.org/10.1038/s41531-023-00505-0
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