Zinc and metformin co-functionalized polyetheretherketone: A novel dental implant material tailored for the elderly

Introduction: The rising demand for dental implants among the elderly population is challenged by age-related impairments in osteogenic regeneration, such as Wnt/β-catenin signaling decline, ROS-mediated cellular senescence (compromising osteoblast differentiation), and elevated pro-inflammatory cyt...

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Hauptverfasser:	Zhengwei Liu, Enze Zhao, Yansong Wang, Hanwei Huang, Yuxun Wu, Yichong He, Shuting Bai, Suwen Wang, Shirou Fan, Shuaishuai Cao, Bin Tang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-06-01
Schriftenreihe:	Journal of Advanced Research
Schlagworte:	Dental implant Polyetheretherketone Osseointegration Osteoblast senescence Surface modification
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S209012322500671X
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