Recombinant human milk fat globule-EGF factor VIII (rhMFG-E8) as a therapy for sepsis after acute exposure to alcohol

Abstract Background Alcohol intake predisposes to infections and sepsis. Alcohol and sepsis inhibit the expression of milk fat globule epidermal growth factor-factor VIII (MFG-E8), a glycoprotein essential for optimal efferocytosis, resulting in the release of proinflammatory molecules and increased...

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Detalhes bibliográficos

Principais autores:	Wayne W. Chaung, Max Brenner, Hao-Ting Yen, Mahendar L. Ochani, Asha Jacob, Ping Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-11-01
coleção:	Molecular Medicine
Assuntos:	Alcohol Sepsis CLP rhMFG-E8 Survival Therapy
Acesso em linha:	http://link.springer.com/article/10.1186/s10020-019-0118-x
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