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Development and validation of a disulfidptosis-related scoring system to predict clinical outcome and immunotherapy response in acute myeloid leukemia by integrated analysis of single-cell and bulk RNA-sequencing

Background: Disulfidptosis is a metabolically relevant mode of cell death, and its relationship with acute myeloid leukemia (AML) has not been clarified. In this study, disulfidptosis scores were computed to examine the potential biological mechanisms.Methods: Consensus clustering was applied to det...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Fangmin Zhong, Junyao Jiang, Fang-Yi Yao, Jing Liu, Xu Shuai, Xin-Lu Wang, Bo Huang, Xiaozhong Wang
التنسيق: Artigo
اللغة:Inglês
منشور في: Frontiers Media S.A. 2023-11-01
سلاسل:Frontiers in Pharmacology
الموضوعات:
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fphar.2023.1272701/full
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