Global matrisome changes in obese lung are linked to fibroblastic stroma and premature aging

Summary: Obesity is linked to an increased risk of various lung disorders, yet its role in disease progression remains poorly understood. We have utilized multiomics approaches together with functional assays to explore the effect of obesity on the lung. Obesity induced matrisome remodeling and stru...

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Hlavní autoři:	Sophia Rottmann, Jian Li, Jelena Zurkovic, Pablo S. Bravo, Andreas U. Lindner, Jie Qin, Sebastian Kallabis, Qi Mei, Xiansheng Liu, Christoph Thiele, Christoph Eckert, Felix Meissner, Veronika Lukacs-Kornek
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-09-01
Edice:	Cell Reports
Témata:	CP: Metabolism
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124725010563
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